The hidden base of the iceberg: gut peptidoglycome dynamics is foundational to its influence on the host
The intestinal microbiota of humans includes a highly diverse range of bacterial species.All these bacteria possess a cell wall, composed primarily of the macromolecule peptidoglycan.As such, the gut also harbors an abundant and varied peptidoglycome.A remarkable range of host physiological pathways are regulated by peptidoglycan fragments that ori